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Death Domain Database

Protein or complex
PDB ID
Residues
3D structure
Source Organism
Resolution (Å)
Unitprot
Method
Publication
AIM2 PYD
2N00
1-95
2N00-3D
Mus musculus
-
Q91VJ1
NMR
2015-Hou
AIM2 PYD F27G
4O7Q
0-93*
4O7Q-3D
Homo sapiens
1.8
O14862
X-RAY
2014-Lu
AIM2 PYD filament
7K3R
1-95
7K3R-3D
Homo sapiens
3.2
O14862
EM
2021-Matyszewski
AIM2 PYD with MBP (color CARD domain and leave others in gray)
3VD8
2-335
3VD8-3D
Escherichia coli O157:H7, Homo sapiens
2.1
O14862, P0AEY0
X-RAY
2013-Jin
APAF-1 CARD
1C15
1-97
1C15-3D
Homo sapiens
-
O14727
NMR
1999-Zhou
APAF-1 CARD
1CY5
1-92
1CY5-3D
Homo sapiens
1.3
O14727
X-RAY
1999-Vaughn
APAF-1 CARD
1CWW
5-97
1CWW-3D
Homo sapiens
-
O14727
NMR
1999-Day
APAF-1 CARD
2YGS
1-91
2YGS-3D
Homo sapiens
1.6
O14727
X-RAY
1999-Qin
APAF-1 CARD: Caspase-9 CARD (color CARD domain and leave others in gray)
3YGS
1-95
3YGS-3D
Homo sapiens
2.5
O14727, P55211
X-RAY
1999-Qin
ARC CARD
4UZ0
*
4UZO-3D
Homo sapiens
2.4
O60936
X-RAY
2015-Jang
ASC CARD
5GPQ
2-461
5GPQ-3D
Escherichia coli O157:H7, Danio rerio
2.1
P0AEX9, Q9I9N6
X-RAY
2018-Li
ASC CARD filament
6K99
112-194
6K99-3D
Homo sapiens
4.1
Q9ULZ3
EM
2021-Gong
ASC PYD
5GPP
2-462
5GPP-3D
Escherichia coli O157:H7, Danio rerio
2
P0AEX9, Q9I9N6
X-RAY
2018-Li
ASC PYD
1UCP
1-91
1UCP-3D
Homo sapiens
-
Q9ULZ3
NMR
2003-Liepinsh
ASC PYD CARD
2KN6
1-195
2KN6-3D
Homo sapiens
-
Q9ULZ3
NMR
2009-de Alba
ASC PYD filament
2N1F
2-90
2N1F-3D
Mus musculus
4
Q9EPB4
ssNMR, EM
2015-Sborgi
ASC PYD filament
3J63
1-91
3J63-3D
Homo sapiens
3.8
Q9ULZ3
EM
2014-Lu
ASC-CARD filament
6N1H
112-194
6N1H-3D
Homo sapiens
3.2
Q9ULZ3
EM
2018-Li
ASC2
2HM2
1-89
2HM2-3D
Homo sapiens
-
Q8WXC3
NMR
2006-Natarajan
Ankryn-1 DD
2YVI
1397-1485
2YVI-3D
Homo sapiens
1.9
P16157
X-RAY
-
Ankyrin G DD
4O6X
2-101
4O6X-3D
Homo sapiens
2.1
Q12955
X-RAY
2014-Liu
Ankyrin-1 DD
2YQF
1387-1497
2YQF-3D
Homo sapiens
-
P16157
NMR
-
Ankyrin-B DD (color DD and leave others in gray)
4D8O
*
4D8O-3D
Homo sapiens
2.2
Q01484
X-RAY
2012-Wang
Apaf from Biortus. (color CARD and leave others gray)
8XQK
*
8XQK-3D
Homo sapiens
2.9
O14727
X-RAY
-
Apaf-1 CARD
2P1H
1-94
2P1H-3D
Homo sapiens
1.6
O14727
X-RAY
2007-Milam
Apaf-1 CARD: caspase-9 CARD
4RHW
1-95
4RHW-3D
Homo sapiens
2.1
O14727, P55211
X-RAY
2014-Hu
Apaf-1 bound to ADP (color CARD domain and leave others in gray)
1Z6T
1-336
1Z6T-3D
Homo sapiens
2.2
O14727
X-RAY
2005-Riedl
Apaf-1-Caspase-9 holoenzyme (color CARD and leave others gray)
5WVE
105-1248
5WVE-3D
Homo sapiens, Equus caballus
4.4
O14727, P55211, P00004(Ec)
EM
2017-Li
Apaf1 CARD: caspase-9 CARD
5WVC
1-95
5WVC-3D
Homo sapiens
3
O14727, P55211
X-RAY
2017-Su
BCL10 CARD - MALT1 DD filament
8CZO
*
8CZO-3D
Homo sapiens
4.3
Q9UDY8, O95999
EM
2022-Xia
BCL10 CARD filament
6BZE
10-115
6BZE-3D
Homo sapiens
4
O95999
EM
2018-David
BCL10 CARD: MALT1 DD filament
6GK2
10-115
6GK2-3D
Homo sapiens
4.9
O95999
EM
2018-Schlauderer
BCL10 R58Q filament
8CZD
10-115
8CZD-3D
Homo sapiens
4.6
O95999
EM
2022-Xia
Bcl10 CARD
2MB9
10-115
2MB9-3D
Homo sapiens
-
O95999
NMR
2013-Qiao
BinCARD CARD
4DWN
3-99
4DWN-3D
Homo sapiens
1.6
Q96LW7
X-RAY
2013-Chen
BinCARD CARD, F16M/L66M
4FH0
2-98
4FH0-3D
Homo sapiens
1.4
Q96LW7
X-RAY
2013-Chen
CARD-only protein
6J52
1-94
6J52-3D
Frog virus 3
2.5
W8SPG9
X-RAY
2019-Kim
CARD8 CARD
4IKM
1-463
4IKM-3D
Escherichia coli K-12, Homo sapiens
2.5
P0AEX9, Q9Y2G2
X-RAY
2013-Jin
CARD8 CARD filament
6XKJ
451-535
6XKJ-3D
Homo sapiens
3.5
Q9Y2G2
EM
2021-Robert Hollingsworth
CARD8 filament
6K9F
451-537
6K9F-3D
Homo sapiens
3.7
Q9Y2G2
EM
2021-Gong
CARD9 CARD dimer
6N2M
1-142
6N2M-3D
Homo sapiens
-
Q9H257
NMR
2019-Holliday
CARD9 CARD domain-swapped dimer
6E28.
2-97
6E28-3D
Homo sapiens
1.4
Q9H257
X-RAY
2018-Holliday
CARD9 CARD filament
6N2P
8-95
6N2P-3D
Homo sapiens
4
Q9H257
EM
2019-Holliday
CARD9 CARD, domain-swapped dimer
6E27.
3-97
6E27-3D
Homo sapiens
1.8
Q9H257
X-RAY
2018-Holliday
CARMA1 CARD
4I16
20-109
4I16-3D
Mus musculus
1.8
Q8CIS0
X-RAY
2012-Li
CARMA1 CARD
4JUP
22-108
4JUP-3D
Homo sapiens
3.2
Q9BXL7
X-RAY
2013-Jang
CARMA1 CARD
4LWD
21-110
4LWD-3D
Homo sapiens
1.8
Q9BXL7
X-RAY
2013-Qiao
CED-4 Apoptosome (color CARD domain and leave others in gray)
3LQQ
*
3LQQ-3D
Caenorhabditis elegans
3.5
P30429
X-RAY
2010-Qi
CED-4 hexamer
8JNS
*
8JNS-3D
Caenorhabditis elegans
4.2
P30429
EM
2023-Li
CED-4: CED-3 (color CARD and leave others gray)
8JO0
1-110
8JO0-3D
Caenorhabditis elegans
3.6
P30429
EM
2023-Li
CED-4: CED-3 (color DED and leave others in gray)
4M9X
*
4M9X-3D
Caenorhabditis elegans
3.3
P30429
X-RAY
2013-Huang
CED-4: CED-3 (color DED and leave others in gray)
4M9Z
*
4M9Z-3D
Caenorhabditis elegans
3.4
P30429
X-RAY
2013-Huang
CED-4: CED-3 (color DED and leave others in gray)
4M9Y
*
4M9Y-3D
Caenorhabditis elegans
4.2
P30429
X-RAY
2013-Huang
CED-4: CED-3 (color DED and leave others in gray)
4M9S
*
4M9S-3D
Caenorhabditis elegans
3.2
P30429
X-RAY
2013-Huang
CED-4: CED-9 (color CARD domain and leave others in gray)
2A5Y
67-241
2A5Y-3D
Caenorhabditis elegans
2.6
P41958, P30429
X-RAY
2005-Yan
CED-4:CED-3 complex (color CARD domain and leave others in gray)
3LQR
*
3LQR-3D
Caenorhabditis elegans
3.9
P30429
X-RAY
2010-Qi
CFLAR tandem DED
6M6O
1-185
6M6O-3D
Homo sapiens
-
O15519
NMR
2022-Bai
Casp-8 tDED filament
5L08
2-182
5L08-3D
Homo sapiens
4.6
Q14790
EM
2016-Fu
Caspase-1 CARD filament
5FNA
1-85
5FNA-3D
Homo sapiens
4.8
P29466
EM
2016-Lu
Caspase-1 CARD: ASC CARD octamer
7KEU
2-86
7KEU-3D
Homo sapiens
3.9
P29466, Q9ULZ3
EM
2021-Robert Hollingsworth
Caspase-8 2DED
4ZBW
3-184
4ZBW-3D
Homo sapiens
2.2
Q14790
X-RAY
2015-Shen
Caspase-8 isoform B DED
7LVM
1-185
7LVM-3D
Homo sapiens
1.5
Q14790
X-RAY
2022-Ansalone
Caspase-8 isoform G DED
7LVJ
60-244
7LVJ-3D
Homo sapiens
1.5
Q14790
X-RAY
2022-Ansalone
Caspase-8 tDED
6AGW
2-180
6AGW-3D
Homo sapiens
2.1
Q14790
X-RAY
2019-Park
Caspase-8 tDED dimer
5H33
2-182
5H33-3D
Homo sapiens
3.6
Q14790
X-RAY
-
Caspase-8 tDED dimer
5H31
2-183
5H31-3D
Homo sapiens
3.2
Q14790
X-RAY
-
Caspase8 tDED
5JQE
18-1182
5JQE-3D
Escherichia coli
3.2
P0AEX9, Q14790
X-RAY
2016-Fu
DARK Drosophila apoptosome (color CARD and leave others gray)
4V4L
*
4V4L-3D
Drosophila melanogaster
6.9
Q7KLI1
EM
2011-Yuan
DR3 DD
5YEV
2-254
5YEV-3D
Mus musculus
2.5
P0AEX9, Q93038
X-RAY
2019-Yin
DR3 DD
5YGS
2-457
5YGS-3D
Homo sapiens
2.7
P0AEX9, Q93038
X-RAY
2019-Yin
DR3 DD, C363G with MBP (color CARD and leave others gray)
5ZNY
3-450
5ZNY-3D
Escherichia coli K-12, Mus musculus
2.7
B1AWN9, P0AEX9
X-RAY
2019-Yin
DR3 DD, D412E
5YGP
4-456
5YGP-3D
Homo sapiens
2.1
P0AEX9, Q93038
X-RAY
2019-Yin
DR3 DD, I387V with MBP (color CARD and leave others gray)
5ZNZ
3-451
5ZNZ-3D
Escherichia coli K-12, Mus musculus
2.6
B1AWN9, P0AEX9
X-RAY
2019-Yin
DR6 DD
2DBH
1-102
2DBH-3D
Homo sapiens
-
O75509
NMR
-
Dark apoptosome from Drosophila melanogaster (color CARD domain and leave others in gray)
3J9L
*
3J9L-3D
Drosophila melanogaster
4
Q7KLI1
EM
2015-Pang
Dark apoptosome in complex with Dronc CARD domain (color CARD domain and leave others in gray)
3J9K
*
3J9K-3D
Drosophila melanogaster
4.1
Q7KLI1, Q9XYF4
EM
2015-Pang
Designed protein
7VTY
3-92
7VTY-3D
synthetic construct
2.5
X-RAY
2023-Zhang
Designed protein similar to Apaf-1 CARD
6JCC
-2-94*
6JCC-3D
synthetic construct
1.5
X-RAY
-
FADD DD
1FAD
89-183
1FAD-3D
Mus musculus
-
Q61160
NMR
1999-Jeong
FADD DD
1E3Y
89-192
1E3Y-3D
Homo sapiens
-
Q13158
NMR
2000-Berglund
FADD DD
1E41.
89-192
1E41-3D
Homo sapiens
-
Q13158
NMR
2000-Berglund
FADD DD: NleB (color DD and leave others gray)
6ACI
-1-329*
6ACI-3D
Escherichia coli O127:H6 str. E2348/69, Homo sapiens
1.9
B7UI21, Q13158
X-RAY
2019-Ding
FADD DED, F25G
1A1Z
1-83
1A1Z-3D
Homo sapiens
-
Q13158
NMR
1998-Eberstadt
FADD DED, F25Y
1A1W
1-83
1A1W-3D
Homo sapiens
-
Q13158
NMR
1998-Eberstadt
FADD: Caspase-8: cFLIP DED
8YBX
2-182
8YBX-3D
Homo sapiens
3.7
Q14790, O15519, Q13158
EM
2024-Yang
FADD: Caspase-8: cFLIP DED
8YD8
*
8YD8-3D
Homo sapiens
3.1
O15519, Q14790, Q13158
X-RAY
2024-Yang
FADD: Caspase-8: cFLIP DED
8YD7
*
8YD7-3D
Homo sapiens
3.3
O15519, Q14790, Q13158
X-RAY
2024-Yang
FAS DD
1DDF
201-327
1DDF-3D
Homo sapiens
-
P25445
NMR
1996-Huang
FAS DD: FADD (5-7:5)
3OQ9
223-308
3OQ9-3D
Mus musculus, Homo sapiens
6.8
P25446, Q13158
X-RAY
2010-Wang
FEM1B
6LBF
*
6LBF-3D
Homo sapiens
3.3
Q9UK73
X-RAY
2021-Chen
Fas DD: FADD DD (4:4)
3EZQ
223-337
3EZQ-3D
Homo sapiens
2.7
P25445, Q13158
X-RAY
2009-Scott
GBP CARD with MBP (color CARD domain and leave others in gray)
4IRL
1-462
4IRL-3D
Escherichia coli K-12, Danio rerio
1.5
B0V1H4, P0AEX9
X-RAY
2013-Jin
ICEBERG CARD
1DGN
2-90
1DGN-3D
Homo sapiens
-
P57730
NMR
2000-Humke
IRAK-M DD R56D, Y61E
5UKE
1-124
5UKE-3D
Homo sapiens
-
Q9Y616
NMR
2018-Nechama
IRAK4 DD
2A9I
3-107
2A9I-3D
Mus musculus
1.7
Q8R4K2
X-RAY
2005-Lasker
IRAK4 DD
1WH4
1-127
1WH4-3D
Mus musculus
-
Q8R4K2
NMR
-
Ifi205b PYD
2YU0
1-94
2YU0-3D
Mus musculus
-
P0DOV1
NMR
-
K63-polyUb MDA5CARDs complex (color DD and leave others gray)
7DNJ
4-200
7DNJ-3D
Homo sapiens
3.3
Q9BYX4, P0CG47
EM
2021-Song
MALT1 DD
2G7R
*
2G7R-3D
Homo sapiens
2.7
Q9UDY8
X-RAY
-
MALT1 death domain
8J5I
28-124
8J5I-3D
Homo sapiens
2.1
Q9UDY8
X-RAY
-
MAVS CARD
2MS8
-1-100*
2MS8-3D
Homo sapiens
-
Q7Z434
NMR
2016-He
MAVS CARD E26R
4O9L
-1-94*
4O9L-3D
Equus caballus
1.9
F6QPU3
X-RAY
2014-Xu
MAVS CARD R64C
4O9F
1-94
4O9F-3D
Equus caballus
2.3
F6QPU3
X-RAY
2014-Xu
MAVS CARD filament
3J6C
370-462
3J6C-3D
Homo sapiens
9.6
Q7Z434
EM
2014-Xu
MAVS CARD filament
3J6J
1-97
3J6J-3D
Homo sapiens
3.6
Q7Z434
EM
2014-Wu
MAVS CARD filament
2MS7
-1-100*
2MS7-3D
Homo sapiens
-
Q7Z434
ssNMR
2016-He
MC159 tandem DED
2BBZ
2-191
2BBZ-3D
Molluscum contagiosum virus subtype 1
3.8
Q98325
X-RAY
2005-Yang
MC159 tandem DED
2F1S
7-183
2F1S-3D
Molluscum contagiosum virus subtype 1
1.4
Q98325
X-RAY
2006-Li
MC159 tandem DED
2BBR
*
2BBR-3D
Molluscum contagiosum virus subtype 1
1.2
Q98325
X-RAY
2005-Yang
MDA5 tCARD: MAVS CARD: polyUb (color CARD and leave others gray)
7DNI
1-73
7DNI-3D
Homo sapiens
3.2
P0CG47, Q9BYX4, Q7Z434
EM
2021-Song
MNDA PYD
2DBG
1-103
2DBG-3D
Homo sapiens
-
P41218
NMR
-
MNDA PYD with MBP
5H7Q
2-470
5H7Q-3D
Homo sapiens
1.5
P0AEX9, P41218
X-RAY
2017-Jin
MNDA PYD with MBP
5WPZ
1-460
5WPZ-3D
Homo sapiens
2
P0AEX9, P41218
X-RAY
2017-Jin
MyD88 DD filament
6I3N
19-121
6I3N-3D
Homo sapiens
3.1
Q99836
EM
2020-Moncrieffe
MyD88 DD: IRAK4 DD: IRAK2 DD (6:4:4)
3MOP
19-123
3MOP-3D
Homo sapiens
3.4
Q99836, Q9NWZ3, O43187
X-RAY
2010-Lin
NALP1 PYD
1PN5
59-151
1PN5-3D
Homo sapiens
-
P06654, Q9C000
NMR
2003-Hiller
NALP10 PYD
2DO9
1-115
2DO9-3D
Mus musculus
-
Q8CCN1
NMR
-
NALP3 PYD
3QF2
5-94
3QF2-3D
Homo sapiens
1.7
Q96P20
X-RAY
2011-Bae
NLRC4 CARD filament
6K8J
1-85
6K8J-3D
Homo sapiens
3.3
Q9NPP4
EM
2021-Gong
NLRC4 CARD filament
6MKS
1-90
6MKS-3D
Homo sapiens, Vaccinia virus
3.4
P42212, Q9NPP4
EM
2018-Matyszewski
NLRC4-CARD filament
6N1I
1-85
6N1I-3D
Homo sapiens
3.6
Q9NPP4
EM
2018-Li
NLRC5 CARD
2MJM
1-101
2MJM-3D
Mus musculus
-
C3VPR6
NMR
2014-Gutte
NLRP1 CARD
3KAT
1379-1462
3KAT-3D
Homo sapiens
3.1
Q9C000
X-RAY
-
NLRP1 CARD
4IFP
2-459
4IFP-3D
Escherichia coli K-12, Homo sapiens
2
P0AEX9, Q9C000
X-RAY
2013-Jin
NLRP1 CARD filament
6XKK
1379-1463
6XKK-3D
Homo sapiens
3.7
Q9C000
EM
2021-Robert Hollingsworth
NLRP1 CARD filament
6K7V
1379-1462
6K7V-3D
Homo sapiens
3.7
Q9C000
EM
2021-Gong
NLRP10 PYD
2M5V
1-102
2M5V-3D
Homo sapiens
-
Q86W26
NMR
2013-Su
NLRP12 PYD
4XHS
1-458
4XHS-3D
Escherichia coli O157:H7, Homo sapiens
1.7
P0AEX9
X-RAY
-
NLRP12 PYD
2L6A
1-102
2L6A-3D
Homo sapiens
-
P59046
NMR
2011-Pinheiro
NLRP12 PYD with MBP
5H7N
2-460
5H7N-3D
Homo sapiens
1.8
P0AEX9, P59046
X-RAY
2017-Jin
NLRP14 PYD
4N1L
7-101
4N1L-3D
Homo sapiens
2
Q86W24
X-RAY
2014-Eibl
NLRP14 PYD
4N1K
6-93
4N1K-3D
Homo sapiens
3
Q86W24
X-RAY
2014-Eibl
NLRP14 PYD
4N1J
6-96
4N1J-3D
Homo sapiens
2.6
Q86W24
X-RAY
2014-Eibl
NLRP3 PYD
2NAQ
1-91
2NAQ-3D
Homo sapiens
-
Q96P20
NMR
2016-Oroz
NLRP3 PYD filament
7PZD
3-94
7PZD-3D
Homo sapiens
3.6
Q96P20
EM
2022-Hochheiser
NLRP3 PYD filament
8ERT
1-95
8ERT-3D
Homo sapiens
3.3
Q96P20
EM
2023-Xiao
NLRP4 PYD
4EWI
5-95
4EWI-3D
Homo sapiens
2.3
Q96MN2
X-RAY
2012-Eibl
NLRP6 PYD filament
6NCV
14-104
6NCV-3D
Homo sapiens
3.7
P59044
EM
2019-Shen
NLRP6 PYD, with MBP
6NDJ
15-1086
6NDJ-3D
Escherichia coli K-12, Homo sapiens
2.3
P0AEX9, P59044
X-RAY
2019-Shen
NLRP7 Pyrin domain
2KM6
3-98
2KM6-3D
Homo sapiens
-
Q8WX94
NMR
2010-Pinheiro
NLRP9 PYD
6Z2G
9-97
6Z2G-3D
Homo sapiens
2
Q7RTR0
X-RAY
2020-Marleaux
NLRP9 PYD
7BSO
5-97
7BSO-3D
Homo sapiens
2.1
Q7RTR0
X-RAY
2020-Ha
NOD1 CARD
2B1W
12-110
2B1W-3D
Homo sapiens
-
Q9Y239
NMR
2007-Manon
NOD1 CARD
2DBD
1-107
2DBD-3D
Homo sapiens
-
Q9Y239
NMR
-
NOD1 CARD
2NZ7
1-148
2N27-3D
Homo sapiens
1.9
Q9Y239
X-RAY
2008-Srimathi
NOD1 CARD
2NSN
16-110
2NSN-3D
Homo sapiens
2
Q9Y239
X-RAY
2007-Coussens
NOD1 CARD domain swapped dimer
4E9M
14-110
4E9M-3D
Homo sapiens
2.2
Q9Y239
X-RAY
-
NRADD DD
6HJ7
145-246
6HJ7-3D
Mus musculus
-
Q8CJ26
NMR
2019-Nadezhdin
PEA-15 DED
1N3K
1-130
1N3K-3D
Cricetulus griseus
-
Q9Z297
NMR
2002-Hill
PEA-15 DED
6P6B
1-90
6P6B-3D
Homo sapiens
-
Q15121
NMR
2019-Crespo-Flores
PEA-15 DED
2LS7
1-90
2LS7-3D
Mus musculus
-
Q62048
NMR
2012-Twomey
PEA-15 DED: Dually Phosphorylated ERK2 (color DED and leave others in gray)
4IZA
11-358
4IZA-3D
Homo sapiens
1.9
P28482,Q15121
X-RAY
2013-Mace
PEA-15 DED: ERK2
6P6C
1-90
6P6C-3D
Homo sapiens
-
Q15121
NMR
2019-Crespo-Flores
PEA-15 DED: ERK2 phosphomimetic mutant (color DED and leave others in gray)
4IZ5
11-357
4IZ5-3D
Homo sapiens
3.2
P28482, Q15121
X-RAY
2013-Mace
PEA-15 DED: Non-Phosphorylated ERK2 (color DED and leave others in gray)
4IZ7
11-359
4IZ7-3D
Homo sapiens, Cricetulus griseus
1.8
P28482, Q9Z297
X-RAY
2013-Mace
PELLE DD: TUBE DD
1D2Z
28-129
1D2Z-3D
Drosophila melanogaster
2
Q05652, P22812
X-RAY
1999-Xiao
PIDD DD: RAIDD DD
2OF5
109-199
2OF5-3D
Homo sapiens
3.2
P78560, Q9HB75
X-RAY
2007-Park
PYD filament of AIM2
6MB2
0-93
6MB2-3D
Homo sapiens, Aequorea victoria
5
O14862, P42212
EM
2015-Lu
Pelle DD
1YGO
1-110
1YGO-3D
Drosophila melanogaster
-
Q05652
NMR
2005-Moncrieffe
Pelle DD
1IK7
78-129
1IK7-3D
Drosophila melanogaster
2.3
Q05652
X-RAY
2002-Xiao
Pyrin PYD
2MPC
4-93
2MPC-3D
Homo sapiens
-
O15553
NMR
2014-Vajjhala
RAIDD CARD
3CRD
1-100
3CRD-3D
Homo sapiens
-
P78560
NMR
1998-Chou
RAIDD DD
2O71
109-199
2O71-3D
Homo sapiens
2
P78560
X-RAY
2006-Park
RIG-I second CARD
2LWD
95-190
2LWD-3D
Homo sapiens
-
O95786
NMR
2012-Ferrage
RIG-I second CARD T170E
2LWE
95-190
2LWE-3D
Homo sapiens
-
O95786
NMR
2012-Ferrage
RIG-I tCARD
6BZH
-2-188*
6BZH-3D
Mus musculus
2.5
Q6Q899
X-RAY
2018-D'Cruz
RIG-I tamdem CARD: ubiquitin (color tandem CARD and leave ubiquitin gray)
4NQK
1-187
4NQK-3D
Homo sapiens
3.7
O95786, P0CG48
X-RAY
2014-Peisley
RIG-I tandem CARD (color CARD domain and leave others in gray)
4A2W
*
4A2W-3D
Anas platyrhynchos
3.7
D3TI84
X-RAY
2011-Kowalinkski
RIG-I tandem CARD (color CARD domain and leave others in gray)
4A2Q
*
4A2Q-3D
Anas platyrhynchos
3.4
D3TI84
X-RAY
2011-Kowalinkski
RIG-I tandem CARD: MAVS CARD
4P4H
1-188
4P4H-3D
Homo sapiens
3.4
O95786, Q7Z434, P62987
X-RAY
2014-Wu
RIP2 CARD
5YRN
430-516
5YRN-3D
Homo sapiens
4.1
O43353
EM
2018-Gong
RIP2 CARD filament
6GGS
433-518
6GGS-3D
Homo sapiens
3.9
O43353
EM
2018-Pellegrini
RIP2 CARD, with MBP
6GFJ
2-458
6GFJ-3D
Methanosarcina mazei, Homo sapiens
3.3
O43353
X-RAY
2018-Pellegrini
RIPK1 DD, GlcNAcylated
6AC5
574-670
6AC5-3D
Homo sapiens
1.5
Q13546
X-RAY
2019-Ding
TNFR1 DD
1ICH
327-412
1ICH-3D
Homo sapiens
-
P19438
NMR
2001-Sukits
TRADD DD
5XME
199-312
5XME-3D
Homo sapiens
-
Q15628
NMR
2017-Zhang
TRADD DD, GlcNAcylated
6AC0
198-312
6AC0-3D
Homo sapiens
1.4
Q15628
X-RAY
2019-Ding
UNC5H2 DD
1WMG
854-943
1WMG-3D
Mus musculus
2.1
Q8K1S3
X-RAY
2006-Handa
UNC5b DD (color DD and leave others in gray)
3G5B
*
3G5B-3D
Rattus norvegicus
2
O08722
X-RAY
2009-Wang
apoptosome with procaspase-9 (color CARD and leave others gray)
5JUY
*
5JUY-3D
Homo sapiens
4.1
O14727, P55211, P62894(Bos)
EM
2016-Cheng
cFLAR tDED
7DEE
1-185
7DEE-3D
Homo sapiens
-
O15519
NMR
2020-Bai
cFLIP DED1
7LXC
1-88
7LXC-3D
Homo sapiens
-
O15519, Q13158
NMR
2022-Panaitiu
cIAP1 CARD
2L9M
431-562
2L9M-3D
Homo sapiens
-
Q13490
NMR
2011-Lopez
cIAP1 CARD (color CARD domain and leave others in gray)
3T6P
*
3T6P-3D
Homo sapiens
1.9
Q13490
X-RAY
2011-Dueber
cPOP1 PYD
4QOB
3-89
4QOB-3D
Homo sapiens
2.7
Q8WXC3
X-RAY
-
caspase-11-CARD
6KXG
*
6KXG-3D
Mus musculus
2.8
P0AEX9
X-RAY
2020-Liu
hMNDA-PYD with MBP
5WQ6
2-468
5WQ6-3D
Homo sapiens
1.6
P0AEX9
X-RAY
2017-Jin
intact FADD (MORT1)
2GF5
1-191
2GF5-3D
Homo sapiens
-
Q13158
NMR
2006-Carrington
p100 DD
2D96
1-109
2D96-3D
Homo sapiens
-
Q00653
NMR
-
p105 DD
2DBF
1-100
2DBF-3D
Homo sapiens
-
P19838
NMR
-
p45 Death Domain
2IB1
138-228
2IB1-3D
Mus musculus
-
Q8CJ26
NMR
-
p75NTR DD
4F42
2-85
4F42-3D
Rattus norvegicus
2.4
P07174
X-RAY
-
p75NTR DD
1NGR
334-418
1NGR-3D
Rattus norvegicus
-
P07174
NMR
1997-Liepinsh
p75NTR DD
4F44
3-85
4F44-3D
Rattus norvegicus
2.4
P07174
X-RAY
-
p75NTR DD dimer
2N97
334-427
2N97-3D
Homo sapiens
-
P08138
NMR
2015-Lin
p75NTR DD: RhoGDI
2N80
334-427
2N80-3D
Homo sapiens
-
P08138,P52565
NMR
2015-Lin
p75NTR DD: TRADD DD
7CSQ
330-427
7CSQ-3D
Homo sapiens
-
P08138, Q15628
NMR
2021-Zhang
p75NTR DD:RIP2 CARD
2N83
334-427
2N83-3D
Homo sapiens
-
P08138, O43353
NMR
2015-Lin
p84 DD
1WXP
1-110
1WXP-3D
Homo sapiens
-
Q96FV9
NMR
-
vFLIP tDED, R12E
7PDJ
*
7PDJ-3D
Human gammaherpesvirus 8
4.2
F5HEZ4
X-RAY
2022-Bagneris
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